Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | FDPS | P14324 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4760882 | 0.75 | NPC1 (0.54) | NPC1LMNAALOX15TSHRMAPK1 | |
| SCHEMBL7973829 | 0.75 | NPC1 (0.54) | NPC1LMNAALOX15TSHRMAPK1 | |
| SCHEMBL11761155 | 0.75 | NPC1 (0.72) | NPC1LMNAALOX15TSHRMAPK1 | |
| SCHEMBL10013763 | 0.74 | NPC1 (0.81) | NPC1LMNAALOX15TSHRMAPK1 | |
| SCHEMBL6676718 | 0.73 | LTA4H (0.62) | LTA4HFDPSBCHEACHEKDM4E | |
| SCHEMBL11588763 | 0.73 | NPC1 (0.55) | NPC1LMNAALOX15TSHRMAPK1 | |
| SCHEMBL465562 | 0.73 | LTA4H (0.59) | NPC1LMNAALOX15TSHRMAPK1 | |
| SCHEMBL9309350 | 0.72 | NPC1 (0.59) | NPC1LMNAALOX15TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL9248996 | 0.72 | LTA4H (0.60) | NPC1LMNAALOX15TSHRMAPK1 | |
| SCHEMBL10617099 | 0.71 | L3MBTL1 (0.54) | LTA4HRECQLL3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988828-A | Antiulcer agents, antagonist for histamine H2 receptors | FUJIREBIO KABUSHIKI KAISHA (JP) | 1991-01-29 | — | — | US | disclosed |
| EP-0318036-A2 | Phenoxypropyl derivatives | FUJIREBIO KABUSHIKI KAISHA (JP) | 1989-05-31 | — | — | EP | disclosed |