Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 14/20 | 0.49 |
| ▸ | ESR1 | P03372 | 11/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | TYMP | P19971 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2706143 | 0.83 | NPC1 (0.52) | NPC1RAB9AMAPTKMT2AKDM4E | |
| SCHEMBL5543997 | 0.80 | NPC1 (0.52) | NPC1RAB9AGAAMAPTUSP2 | |
| SCHEMBL14431592 | 0.80 | GAA (0.54) | NPC1RAB9AGAAMAPTKMT2A | |
| SCHEMBL1557048 | 0.80 | TARBP2 (0.53) | NPC1RAB9AGAAMAPTKMT2A | |
| SCHEMBL5534902 | 0.80 | KDM4E (0.59) | NPC1RAB9AGAAMAPTKMT2A | |
| SCHEMBL24125061 | 0.80 | RAB9A (0.52) | NPC1RAB9AGAAMAPTKMT2A | |
| SCHEMBL436384 | 0.79 | GAA (0.57) | NPC1RAB9AGAAKDM4ENFKB1 | |
| SCHEMBL9097470 | 0.78 | ESR1 (0.50) | NPC1RAB9AESR2ESR1MAPT | |
| SCHEMBL505227 | 0.78 | RAB9A (0.53) | NPC1RAB9AGAAHTTKDM4E | |
| SCHEMBL9863203 | 0.78 | SNCA (0.46) | NPC1RAB9AESR2ESR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002960-A | Viricides for combating picornaviruses | STERLING DRUG, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4939267-A | Viricides | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |
| US-4843087-A | OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES | STERLING DRUG INC. (US) | 1989-06-27 | — | — | US | disclosed |