Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 6/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.40 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10685591 | 0.94 | ALOX15 (0.50) | ALOX15MAPK1HTTESR1ESR2 | |
| SCHEMBL30688233 | 0.94 | ALOX15 (0.50) | ALOX15MAPK1HTTESR1ESR2 | |
| SCHEMBL948481 | 0.92 | ALOX15 (0.61) | ALOX15MAPK1HTTESR1ESR2 | |
| SCHEMBL3656530 | 0.90 | ALOX15 (0.59) | ALOX15MAPK1HTTESR1ESR2 | |
| SCHEMBL5017360 | 0.86 | ALOX15 (0.55) | ALOX15MAPK1HTTESR1ESR2 | |
| SCHEMBL13257366 | 0.85 | ESR1 (0.41) | ALOX15MAPK1HTTESR1ESR2 | |
| SCHEMBL12285444 | 0.84 | ALOX15 (0.53) | ALOX15MAPK1HTTESR1ESR2 | |
| SCHEMBL10902807 | 0.84 | ESR1 (0.53) | ALOX15MAPK1HTTESR1ESR2 | |
| SCHEMBL1023203 | 0.84 | ESR1 (0.47) | ALOX15MAPK1HTTESR1ESR2 | |
| SCHEMBL16865576 | 0.83 | ALOX15 (0.49) | ALOX15MAPK1HTTESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0147653-B1 | HIGH IMPACT POLYPHENYLENE ETHER COMPOSITIONS HAVING IMPROVED PROCESSABILITY | GE CHEMICALS, INC. (US) | 1991-03-20 | — | — | EP | claimed |