Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | ESRRG | P62508 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5523863 | 0.90 | ALOX15 (0.49) | ESR1ESR2ALOX15KLF10MAPK1 | |
| SCHEMBL10902807 | 0.87 | ESR1 (0.53) | ESR1ESR2ALOX15KLF10MAPK1 | |
| SCHEMBL2314239 | 0.87 | ESR1 (0.52) | ESR1ESR2ALOX15KLF10MAPK1 | |
| SCHEMBL10685591 | 0.87 | ALOX15 (0.50) | ESR1ESR2ALOX15KLF10MAPK1 | |
| SCHEMBL30688233 | 0.87 | ALOX15 (0.50) | ESR1ESR2ALOX15KLF10MAPK1 | |
| SCHEMBL249904 | 0.86 | KLF10 (0.53) | ESR1ESR2ALOX15KLF10MAPK1 | |
| SCHEMBL9863223 | 0.85 | ALOX15 (0.53) | ESR1ESR2ALOX15KLF10MAPK1 | |
| SCHEMBL3451808 | 0.84 | KLF10 (0.51) | ESR1ESR2ALOX15KLF10MAPK1 | |
| SCHEMBL12937591 | 0.84 | ALOX15 (0.39) | ESR1ESR2ALOX15KLF10MAPK1 | |
| SCHEMBL1023203 | 0.84 | ESR1 (0.47) | ESR1ESR2ALOX15KLF10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7750190-B2 | reacting hexamethylene tetramine in presence of acid; industrial scale; photoresists | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-07-06 | — | — | US | disclosed |
| US-20090182175-A1 | METHOD FOR PRODUCING NEW POLYNUCLEAR POLY(FORMYLPHENOL) | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090182175-A1 | METHOD FOR PRODUCING NEW POLYNUCLEAR POLY(FORMYLPHENOL) | PCBP1, FPR2, PNKP | ESR1 4141/4885ESR2 2349/4885ALOX15 1248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.