Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9200429 | 0.85 | PLAU (0.49) | POLBHTTNR1I2CYP3A4CYP2D6 | |
| SCHEMBL9862923 | 0.85 | NR1I2 (0.45) | TDP1HTTNR1I2CYP3A4CYP2D6 | |
| SCHEMBL9863026 | 0.84 | KMT2A (0.48) | POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL9863164 | 0.83 | NR1I2 (0.46) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9863009 | 0.82 | CYP3A4 (0.40) | POLBTDP1L3MBTL1NR1I2CYP3A4 | |
| SCHEMBL9706268 | 0.82 | NR1I2 (0.45) | POLBTDP1HTTNR1I2CYP3A4 | |
| SCHEMBL9178754 | 0.82 | CYP2D6 (0.57) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9706270 | 0.80 | KDM4E (0.42) | TDP1NR1I2CYP3A4CYP2D6MEN1 | |
| SCHEMBL10413141 | 0.80 | PLAU (0.51) | POLBHTTNR1I2CYP3A4CYP2D6 | |
| SCHEMBL11034638 | 0.80 | TP53 (0.55) | POLBTDP1HTTTSHRPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002960-A | Viricides for combating picornaviruses | STERLING DRUG, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4939267-A | Viricides | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |
| US-4843087-A | OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES | STERLING DRUG INC. (US) | 1989-06-27 | — | — | US | disclosed |