Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9863105 | 0.86 | CYP2D6 (0.50) | CYP3A4NR1I2CYP2D6ALDH1A1MAPT | |
| SCHEMBL9862958 | 0.84 | NR1I2 (0.41) | CYP3A4NR1I2CYP2D6ALDH1A1MAPT | |
| SCHEMBL9863245 | 0.82 | POLB (0.45) | CYP3A4NR1I2CYP2D6L3MBTL1MEN1 | |
| SCHEMBL9706272 | 0.81 | NR1I2 (0.43) | CYP3A4NR1I2CYP2D6ALDH1A1MAPT | |
| SCHEMBL8615157 | 0.80 | FDPS (0.54) | CYP3A4ALDH1A1FDPSMAPTL3MBTL1 | |
| SCHEMBL6739941 | 0.80 | FDPS (0.54) | CYP3A4ALDH1A1FDPSMAPTL3MBTL1 | |
| SCHEMBL9862928 | 0.79 | ALDH1A1 (0.46) | CYP3A4NR1I2CYP2D6ALDH1A1MAPT | |
| SCHEMBL11030956 | 0.79 | ALDH1A1 (0.46) | CYP3A4NR1I2CYP2D6ALDH1A1MAPT | |
| SCHEMBL9863026 | 0.76 | KMT2A (0.48) | L3MBTL1MEN1KMT2AMAPK1POLB | |
| SCHEMBL9863170 | 0.76 | NR1I2 (0.39) | CYP3A4NR1I2CYP2D6MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002960-A | Viricides for combating picornaviruses | STERLING DRUG, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4939267-A | Viricides | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |
| US-4843087-A | OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES | STERLING DRUG INC. (US) | 1989-06-27 | — | — | US | disclosed |