Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14989194 | 0.74 | PTGS1 (0.47) | LMNAGAAPTGS1PTGS2CYP2C9 | |
| SCHEMBL14989303 | 0.74 | PTGS1 (0.42) | LMNAGAAPTGS1PTGS2CYP2C9 | |
| SCHEMBL594312 | 0.72 | LMNA (0.49) | FBP1LMNAALDH1A1CYP2C9 | |
| SCHEMBL14989186 | 0.70 | PTGS1 (0.39) | FBP1LMNAGAAPTGS1PTGS2 | |
| SCHEMBL29504085 | 0.70 | PTGS1 (0.44) | LMNAGAAPTGS1PTGS2CYP2C9 | |
| SCHEMBL28614233 | 0.70 | PTGS1 (0.44) | LMNAGAAPTGS1PTGS2CYP2C9 | |
| SCHEMBL10356850 | 0.69 | LMNA (0.39) | LMNAALDH1A1CYP2C9MEN1KMT2A | |
| SCHEMBL10434333 | 0.66 | GAA (0.40) | LMNAGAAPTGS1PTGS2CYP2C9 | |
| SCHEMBL15592340 | 0.66 | SMN1; SMN2 (0.40) | LMNAGAAPTGS1PTGS2CYP2C9 | |
| SCHEMBL26088903 | 0.66 | ALDH1A1 (0.41) | FBP1LMNAALDH1A1CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075396-A | Coordination catalyst comprising magnesium, titanium, halogen, aluminum, an organosilicon compound and a heterocyclic diester as electron donor; durability; stereospecific | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-12-24 | — | — | US | disclosed |