Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 6/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.38 |
| ▸ | CTRC | Q99895 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25967516 | 1.00 | PLA2G2C (0.44) | PLA2G2CTLR2PLA2G10PLA2G2ACNR2 | |
| SCHEMBL25909320 | 0.88 | CNR2 (0.36) | PLA2G2CTLR2PLA2G10PLA2G2ACNR2 | |
| SCHEMBL11095547 | 0.87 | PLA2G2C (0.50) | PLA2G2CTLR2PLA2G10PLA2G2APLA2G1B | |
| SCHEMBL11096065 | 0.87 | PLA2G2C (0.50) | PLA2G2CTLR2PLA2G10PLA2G2APLA2G1B | |
| SCHEMBL11042332 | 0.87 | PLA2G2C (0.50) | PLA2G2CTLR2PLA2G10PLA2G2APLA2G1B | |
| SCHEMBL1396102 | 0.87 | LMNA (0.45) | CNR2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4570527 | 0.87 | LPAR1 (0.43) | PLA2G2CTLR2 | |
| SCHEMBL19067483 | 0.86 | LMNA (0.39) | CNR2ALDH1A1GAAPKMLMNA | |
| SCHEMBL9863436 | 0.85 | TLR2 (0.44) | PLA2G2CTLR2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10553671 | 0.84 | PLA2G10 (0.42) | TLR2PLA2G10PLA2G2APLA2G1BPLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5025005-A | Preventive or therapeutic agents for circulatory diseases, allergic disorders; antineoplastic agent; inhibitor for platelet activating factor | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-06-18 | — | — | US | disclosed |
| US-4737518-A | ANTIALLERGENS, ANTINEOPLASTICS, ANTICOAGULANTS, CIRCULATORY DISEASES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-04-12 | — | — | US | disclosed |
| EP-0157609-A2 | Lipid derivatives their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-10-09 | — | — | EP | disclosed |