SCHEMBL25909320

SCHEMBL25909320

CCCCCCCCCCCCCCCCOC(C)C[C@H](COS(=O)(=O)c1ccc(C)cc1)OCc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.36
PLA2G2C Q5R387 1/20 0.36
CTRC Q99895 1/20 0.35
PLA2G10 O15496 1/20 0.35
PLA2G2A P14555 1/20 0.35
CETP P11597 3/20 0.35
MAPT P10636 1/20 0.35
ALDH1A1 P00352 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TLR2 O60603 2/20 0.35
LMNA P02545 1/20 0.34
AR P10275 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9863407 0.88 PLA2G2C (0.44) CNR2PLA2G2CCTRCPLA2G10PLA2G2A
SCHEMBL25967516 0.88 PLA2G2C (0.44) CNR2PLA2G2CCTRCPLA2G10PLA2G2A
SCHEMBL9723718 0.81 PLA2G2C (0.44) PLA2G2CALDH1A1SMN1; SMN2CA1CA2
SCHEMBL9512608 0.81 PLA2G2C (0.44) PLA2G2CALDH1A1SMN1; SMN2CA1CA2
SCHEMBL9488453 0.81 PLA2G2C (0.44) PLA2G2CALDH1A1SMN1; SMN2CA1CA2
SCHEMBL1396102 0.81 LMNA (0.45) CNR2MAPTALDH1A1SMN1; SMN2LMNA
SCHEMBL9723827 0.80 PLA2G2C (0.42) PLA2G2CALDH1A1SMN1; SMN2LMNACA1
SCHEMBL25909329 0.80 PLA2G2C (0.42) CNR2PLA2G2CMAPTALDH1A1LMNA
SCHEMBL19067483 0.79 LMNA (0.39) CNR2MAPTALDH1A1SMN1; SMN2LMNA
SCHEMBL11513138 0.78 CNR2 (0.38) CNR2PLA2G2CCTRCMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230233593-A1 ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS VenatoRx Pharmaceuticals, Inc. 2023-07-27 US disclosed
US-11638715-B2 Orally-bioavailable nucleoside analogs VenatoRx Pharmaceuticals, Inc. (US) 2023-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11638715-B2 Orally-bioavailable nucleoside analogs SLC29A2, SLC29A1, PNP CNR2 3534/4885PLA2G2C 3210/4885CTRC 3479/4885
US-20230233593-A1 ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS SLC29A2, SLC29A1, PNP CNR2 3534/4885PLA2G2C 3210/4885CTRC 3479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.