Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | PRKCA | P17252 | 4/20 | 0.48 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.48 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.48 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10833233 | 0.85 | USP2 (0.49) | USP2PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL1009136 | 0.82 | PRKCA (0.65) | USP2PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL30227320 | 0.82 | USP2 (0.56) | USP2PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL5493689 | 0.82 | PRKCA (0.65) | USP2PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL2732833 | 0.82 | PRKCA (0.65) | USP2PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL7411764 | 0.82 | PRKCA (0.65) | USP2PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL27795601 | 0.82 | PRKCA (0.65) | USP2PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL1008410 | 0.82 | PRKCA (0.65) | USP2PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL6725439 | 0.81 | USP2 (0.54) | USP2PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL10941567 | 0.81 | USP2 (0.54) | USP2PRKCAPRKCEPRKCQPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5025005-A | Preventive or therapeutic agents for circulatory diseases, allergic disorders; antineoplastic agent; inhibitor for platelet activating factor | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-06-18 | — | — | US | disclosed |
| EP-0225129-B1 | PHOSPHOLIPID DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1989-05-24 | — | — | EP | disclosed |
| US-4778912-A | ANTITUMOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-10-18 | — | — | US | disclosed |
| US-4737518-A | ANTIALLERGENS, ANTINEOPLASTICS, ANTICOAGULANTS, CIRCULATORY DISEASES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-04-12 | — | — | US | disclosed |
| EP-0094186-B1 | GLYCEROL DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1986-07-30 | — | — | EP | disclosed |
| US-4576933-A | Method of use of 1-(alkyl for alkylcarbanoyl)-2-carbamoylglycerol derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-03-18 | — | — | US | disclosed |
| EP-0157609-A2 | Lipid derivatives their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-10-09 | — | — | EP | disclosed |
| EP-0094186-A1 | Glycerol derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1983-11-16 | — | — | EP | disclosed |