Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 4/20 | 0.33 |
| ▸ | UBE2M | P61081 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL97698 | 0.87 | GAA (0.39) | ALDH1A1KMT2AGAAMAPTL3MBTL1 | |
| SCHEMBL98718 | 0.78 | GSK3B (0.36) | GSK3BALDH1A1GAAMAOBL3MBTL1 | |
| SCHEMBL171495 | 0.74 | KDM1A (0.34) | GSK3BALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL97922 | 0.74 | PIK3CA (0.43) | GSK3BALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL97709 | 0.73 | CCNE2 (0.41) | GSK3BCASP1MAOB | |
| SCHEMBL98983 | 0.72 | GSK3B (0.36) | GSK3BALDH1A1MAPTMAOBL3MBTL1 | |
| SCHEMBL98560 | 0.72 | GSK3B (0.37) | GSK3BALDH1A1GAAMAPTMAOB | |
| SCHEMBL98972 | 0.72 | YTHDC1 (0.41) | GSK3BMAOB | |
| SCHEMBL99189 | 0.72 | GSK3B (0.38) | GSK3BALDH1A1HSD17B10HPGDMAOB | |
| SCHEMBL98435 | 0.69 | CSF1R (0.41) | GSK3BALDH1A1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426130-B1 | PURINE DERIVATIVE AND ANTITUMOR AGENT USING SAME | ZENYAKU KOGYO KK (JP) | 2015-03-11 | — | — | EP | disclosed |
| EP-2426130-A1 | PURINE DERIVATIVE AND ANTITUMOR AGENT USING SAME | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 2012-03-07 | — | — | EP | disclosed |