Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | DCK | P27707 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 1/20 | 0.32 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL98641 | 0.87 | GSK3B (0.39) | GAAALDH1A1L3MBTL1MAPTMEN1 | |
| SCHEMBL98783 | 0.78 | ALDH1A1 (0.39) | GAAALDH1A1L3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL171639 | 0.75 | PAK4 (0.36) | GAAALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL98098 | 0.74 | PIK3CA (0.49) | GAAALDH1A1L3MBTL1LMNA | |
| SCHEMBL171439 | 0.72 | SMN1; SMN2 (0.35) | ALDH1A1L3MBTL1SMN1; SMN2LMNAMAPT | |
| SCHEMBL97857 | 0.72 | GAA (0.36) | GAAALDH1A1L3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL97697 | 0.72 | CCNE2 (0.42) | GAAMEN1KMT2ATP53 | |
| SCHEMBL97830 | 0.71 | ALDH1A1 (0.34) | GAAALDH1A1L3MBTL1SMN1; SMN2ALOX12 | |
| SCHEMBL98279 | 0.71 | YTHDC1 (0.43) | GAAL3MBTL1SMN1; SMN2TDP1LMNA | |
| SCHEMBL99660 | 0.71 | GAA (0.38) | GAAALDH1A1L3MBTL1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426130-B1 | PURINE DERIVATIVE AND ANTITUMOR AGENT USING SAME | ZENYAKU KOGYO KK (JP) | 2015-03-11 | — | — | EP | disclosed |
| EP-2426130-A1 | PURINE DERIVATIVE AND ANTITUMOR AGENT USING SAME | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 2012-03-07 | — | — | EP | disclosed |