Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2439884 | 0.85 | ALDH1A1 (0.77) | ALDH1A1LMNASLC15A2KDM4EKDM6B | |
| SCHEMBL11041667 | 0.85 | ACE (0.36) | ALDH1A1 | |
| SCHEMBL8155389 | 0.85 | ALDH1A1 (0.77) | ALDH1A1LMNASLC15A2KDM4EKDM6B | |
| SCHEMBL10689700 | 0.83 | ALDH1A1 (0.56) | ALDH1A1LMNASLC15A2KDM4EKDM6B | |
| SCHEMBL28966701 | 0.82 | ALDH1A1 (0.71) | ALDH1A1LMNASLC15A2KDM4EKDM6B | |
| SCHEMBL128923 | 0.82 | — | — | |
| SCHEMBL6932133 | 0.82 | — | — | |
| SCHEMBL6516067 | 0.80 | — | — | |
| SCHEMBL29187674 | 0.78 | ALDH1A1 (0.56) | ALDH1A1LMNASLC15A2KDM4EKDM6B | |
| SCHEMBL8507919 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0191542-B1 | ARYLCYCLOBUTYLALKYL AMINES AND THEIR USE AS ANTIDEPRESSIVE MEDICINES | The Boots Company PLC (GB) | 1988-06-08 | — | — | EP | claimed |
| EP-0191542-A1 | Arylcyclobutylalkyl amines and their use as antidepressive medicines | The Boots Company PLC (GB) | 1986-08-20 | — | — | EP | claimed |
| CN-117413012-A | Silane coupling agent composition and rubber composition containing same | 引能仕株式会社 | 2024-01-16 | — | — | CN | disclosed |
| CN-1318419-C | 1,6,9,14-tetrasubstituted terrylene tetracarboxylic acid diimides | BASF AG (DE) | 2007-05-30 | — | — | CN | disclosed |
| CN-1659167-A | 1,6,9,14-tetrasubstituted terrylene tetracarboxylic acid diimides | BASF AG (DE) | 2005-08-24 | — | — | CN | disclosed |
| US-5047432-A | Antidepressants | THE BOOTS COMPANY PLC (GB) | 1991-09-10 | — | — | US | disclosed |
| CN-1012733-B | Process for the preparation of therapeutic agents | BOOTS CO PLC (GB) | 1991-06-05 | — | — | CN | disclosed |
| US-4925879-A | ANTIDEPRESSANTS | BOOTS COMPANY, PLC (GB) | 1990-05-15 | — | — | US | disclosed |
| EP-0191542-B1 | ARYLCYCLOBUTYLALKYL AMINES AND THEIR USE AS ANTIDEPRESSIVE MEDICINES | The Boots Company PLC (GB) | 1988-06-08 | — | — | EP | disclosed |
| CN-86100954-A | The preparation method of therapeutical agent and application | — | 1986-09-03 | — | — | CN | disclosed |
| EP-0191542-A1 | Arylcyclobutylalkyl amines and their use as antidepressive medicines | The Boots Company PLC (GB) | 1986-08-20 | — | — | EP | disclosed |