1-Naphthol

1-Naphthol

SCHEMBL9864315

Cc1ccccc1N.Oc1cccc2ccccc12

nearest known ligand 0.63

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.63
CYP3A4 P08684 2/20 0.54
TDP1 Q9NUW8 1/20 0.54
ALDH1A1 P00352 3/20 0.52
TSHR P16473 2/20 0.52
HPGD P15428 2/20 0.52
HSD17B10 Q99714 2/20 0.52
KEAP1 Q14145 1/20 0.52
CYP2A6 P11509 1/20 0.52
PLAU P00749 1/20 0.47
CTDSP1 Q9GZU7 1/20 0.47
ALOX15 P16050 1/20 0.45
HSD17B1 P14061 1/20 0.45
HSD17B2 P37059 1/20 0.45
HDAC3 O15379 1/20 0.44
IDO1 P14902 1/20 0.44
EP300 Q09472 1/20 0.44
KAT2B Q92831 1/20 0.44
KAT8 Q9H7Z6 1/20 0.44
NCOR2 Q9Y618 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Naphthol SCHEMBL3836716 0.86 CYP1A2 (0.77) CYP1A2TDP1ALDH1A1TSHRHPGD
1-Naphthol SCHEMBL9403268 0.84 ALDH1A1 (0.74) CYP1A2CYP3A4TDP1ALDH1A1TSHR
O-Tolylamine SCHEMBL22653970 0.84 ALDH1A1 (0.74) CYP1A2CYP3A4TDP1ALDH1A1TSHR
1-Naphthol SCHEMBL2696860 0.84 CYP1A2 (0.74) CYP1A2TDP1ALDH1A1TSHRHPGD
1-Naphthol SCHEMBL8816918 0.84 CYP1A2 (0.74) CYP1A2ALDH1A1TSHRHPGDHSD17B10
1-Naphthol SCHEMBL29209223 0.82 CYP1A2 (0.85) CYP1A2CYP3A4TDP1ALDH1A1TSHR
1-Naphthol SCHEMBL31245624 0.82 CYP1A2 (0.94) CYP1A2CYP3A4TDP1ALDH1A1TSHR
1-Naphthol SCHEMBL11328164 0.81 CYP1A2 (0.68) CYP1A2ALDH1A1TSHRHPGDHSD17B10
O-Tolylamine SCHEMBL10386113 0.80 CYP3A4 (0.68) CYP1A2CYP3A4TDP1ALDH1A1TSHR
1-Naphthol SCHEMBL10627914 0.80 CYP1A2 (0.90) CYP1A2TDP1ALDH1A1TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5008185-A Staining antigen and nuclear material with different stains, measuring and comparing optical density CELL ANALYSIS SYSTEMS, INC. (US) 1991-04-16 US disclosed