1-Naphthol

1-Naphthol

SCHEMBL3836716

Cc1ccccc1C.Oc1cccc2ccccc12

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.77
CYP2A6 P11509 3/20 0.62
ALDH1A1 P00352 2/20 0.62
HSD17B1 P14061 1/20 0.52
HSD17B2 P37059 1/20 0.52
TRPA1 O75762 2/20 0.50
ATM Q13315 1/20 0.50
HPGD P15428 2/20 0.48
HSD17B10 Q99714 2/20 0.48
TSHR P16473 3/20 0.46
PTPN22 Q9Y2R2 1/20 0.46
IDO1 P14902 1/20 0.46
ACHE P22303 1/20 0.46
PLAU P00749 1/20 0.45
KDM4E B2RXH2 1/20 0.45
MAPKAPK2 P49137 1/20 0.45
CTDSP1 Q9GZU7 1/20 0.45
NQO2 P16083 1/20 0.45
MEN1 O00255 1/20 0.45
ESR1 P03372 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Naphthol SCHEMBL8816918 0.93 CYP1A2 (0.74) CYP1A2CYP2A6ALDH1A1HSD17B1HSD17B2
1-Naphthol SCHEMBL2696860 0.93 CYP1A2 (0.74) CYP1A2CYP2A6ALDH1A1HSD17B1HSD17B2
1-Naphthol SCHEMBL11328164 0.90 CYP1A2 (0.68) CYP1A2CYP2A6ALDH1A1HSD17B1HSD17B2
1-Naphthol SCHEMBL10627914 0.88 CYP1A2 (0.90) CYP1A2CYP2A6ALDH1A1HSD17B1HSD17B2
1-Naphthol SCHEMBL273260 0.88 CYP1A2 (1.00) CYP1A2CYP2A6ALDH1A1HSD17B1HSD17B2
1-Naphthol SCHEMBL29767730 0.88 CYP1A2 (1.00) CYP1A2CYP2A6ALDH1A1HSD17B1HSD17B2
1-Naphthol SCHEMBL3416 0.88 CYP1A2 (1.00) CYP1A2CYP2A6ALDH1A1HSD17B1HSD17B2
1-Naphthol SCHEMBL10486461 0.88 CYP1A2 (1.00) CYP1A2CYP2A6ALDH1A1HSD17B1HSD17B2
1-Naphthol SCHEMBL345586 0.88 CYP1A2 (0.65) CYP1A2CYP2A6ALDH1A1HSD17B1HSD17B2
1-Naphthol SCHEMBL9864315 0.86 CYP1A2 (0.63) CYP1A2CYP2A6ALDH1A1HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024135816-A1 REACTIVE GROUP-CONTAINING POLYCARBONATE COMPOUND, NEW SILICONE ELASTOMER PARTICLES USING SAME, COSMETIC MATERIAL COMPOSITION, AND OTHER USE APPLICATION ダウ・東レ株式会社 2024-06-27 WO disclosed
WO-2024135815-A1 RADICAL-POLYMERIZABLE POLYCARBONATE-MODIFIED SILICONE COMPOUND, NOVEL SILICONE/POLYCARBONATE COPOLYMER PARTICLES OBTAINED THEREFROM, AND COSMETIC COMPOSITION AND OTHER USES ダウ・東レ株式会社 2024-06-27 WO disclosed
WO-2024135814-A1 RADICALLY POLYMERIZABLE POLYCAPROLACTONE-MODIFIED SILICONE COMPOUND, NOVEL SILICONE-POLYCAPROLACTONE COPOLYMER PARTICLES AND COSMETIC COMPOSITION USING SAME, AND OTHER USES ダウ・東レ株式会社 2024-06-27 WO disclosed
CN-109153790-B Organosilicon particles, cosmetics, paint and resin containing same 陶氏东丽株式会社 2024-02-20 CN disclosed
CN-114349987-B Organosilicon particles, cosmetics, paint and resin containing same 陶氏东丽株式会社 2023-11-03 CN disclosed
CN-111757917-B Oil-containing silicone elastomer particles and use of cosmetic composition 陶氏东丽株式会社 2022-06-03 CN disclosed
CN-114349987-A Organic silicon particles, and cosmetics, paint and resin compatible with same 陶氏东丽株式会社 2022-04-15 CN disclosed
US-20220073684-A1 SILICONE RESIN-COATED SILICONE ELASTOMER PARTICLES, AND APPLICATIONS THEREOF INCLUDING ORGANIC RESIN ADDITIVES DOW TORAY CO., LTD. (JP) 2022-03-10 US disclosed
EP-3904427-A1 SILICONE RESIN-COATED SILICONE ELASTOMER PARTICLES, AND APPLICATIONS THEREOF INCLUDING ORGANIC RESIN ADDITIVES Dow Toray Co., Ltd. (JP) 2021-11-03 EP disclosed
CN-111757917-A Oil-containing silicone elastomer particles and use of cosmetic composition 陶氏东丽株式会社 2020-10-09 CN disclosed
EP-1478695-B1 SILICONE RESIN COMPOSITION, CURABLE RESIN COMPOSITION, AND CURED RESIN DOW CORNING TORAY CO LTD (JP) 2008-09-24 EP disclosed
CN-101098937-A Silicone resin composition, curable resin composition, and cured resin DOW CORNING TORAY CO LTD (JP) 2008-01-02 CN disclosed
EP-1833917-A1 SILICONE RESIN COMPOSITION, CURABLE RESIN COMPOSITION, AND CURED RESIN Dow Corning Toray Co., Ltd. (JP) 2007-09-19 EP disclosed
US-7138467-B2 Silicone resin composition, curable resin composition, and curable resin DOW CORNING TORAY SILICON CO., LT. (JP) 2006-11-21 US disclosed
WO-2006073056-A1 SILICONE RESIN COMPOSITION, CURABLE RESIN COMPOSITION, AND CURED RESIN DOW CORNING TORAY CO., LTD. (JP) 2006-07-13 WO disclosed
US-20050080204-A1 Silicone resin composition, curable resin composition, and curable resin DOW TORAY CO., LTD. (JP) 2005-04-14 US disclosed
EP-1478695-A1 SILICONE RESIN COMPOSITION, CURABLE RESIN COMPOSITION, AND CURED RESIN Dow Corning Toray Silicone Co., Ltd. (JP) 2004-11-24 EP disclosed
WO-2003072656-A1 SILICONE RESIN COMPOSITION, CURABLE RESIN COMPOSITION, AND CURED RESIN DOW CORNING TORAY SILICONE CO., LTD. (JP) 2003-09-04 WO disclosed
US-6239245-B1 THAT HAS SUPERIOR THERMAL SHOCK RESISTANCE EVEN AFTER ABSORBING MOISTURE. DOW CORNING TORAY SILICONE COMPANY, LTD. (JP) 2001-05-29 US disclosed
EP-1033382-A2 Resin additive, curable resin composition, and cured resin Dow Corning Toray Silicone Company Ltd. (JP) 2000-09-06 EP disclosed