Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 7/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7130147 | 0.81 | PPARD (0.35) | HPGDSMN1; SMN2TRPM8CYP3A4LPAR3 | |
| SCHEMBL18998194 | 0.81 | FAAH (0.41) | HPGDSMN1; SMN2TRPM8CYP3A4GABBR2 | |
| SCHEMBL575551 | 0.80 | FAAH (0.48) | HPGDSMN1; SMN2TRPM8CYP3A4GABBR2 | |
| SCHEMBL18998193 | 0.79 | FAAH (0.39) | HPGDSMN1; SMN2TRPM8CYP3A4GABBR2 | |
| SCHEMBL18998192 | 0.79 | GABBR2 (0.41) | HPGDSMN1; SMN2TRPM8GABBR2GABRR1 | |
| SCHEMBL575224 | 0.78 | TSHR (0.46) | HPGDSMN1; SMN2TRPM8CYP3A4LPAR3 | |
| SCHEMBL5491031 | 0.78 | CYP3A4 (0.50) | HPGDSMN1; SMN2TRPM8CYP3A4GABBR2 | |
| SCHEMBL575549 | 0.76 | CYP3A4 (0.61) | HPGDSMN1; SMN2CYP3A4LPAR3LPAR2 | |
| SCHEMBL575171 | 0.76 | CYP3A4 (0.48) | HPGDSMN1; SMN2TRPM8CYP3A4GABBR2 | |
| SCHEMBL5485224 | 0.76 | CYP3A4 (0.54) | HPGDSMN1; SMN2TRPM8CYP3A4LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068351-A | PROCESS FOR THE PREPARATION OF N OCTAHYDROPENTA (6) PYRROLE CARBOXYLATES | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-26 | — | — | US | disclosed |
| EP-0135182-B1 | PROCESS FOR THE PRODUCTION OF N-ALKYLATED DIPEPTIDES AND OF THEIR ESTERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-27 | — | — | EP | disclosed |
| EP-0135183-B1 | PROCESS FOR THE PREPARATION OF COMPOUNDS CONTAINING CARBOXYLIC ACID AMIDE GROUPS, ESPECIALLY OF PEPTIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-03-30 | — | — | EP | disclosed |
| EP-0056618-B1 | PROCESS FOR PREPARING COMPOUNDS THAT CONTAIN CARBOXYAMIDE GROUPS, ESPECIALLY PEPTIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-08-28 | — | — | EP | disclosed |
| EP-0135182-A2 | Process for the production of N-alkylated dipeptides and of their esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-03-27 | — | — | EP | disclosed |
| EP-0135183-A2 | Process for the preparation of compounds containing carboxylic acid amide groups, especially of peptides | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-03-27 | — | — | EP | disclosed |
| US-4426325-A | Process for the preparation of compounds containing carboxylic acid amide groups, in particular or peptides | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-01-17 | — | — | US | disclosed |
| EP-0056618-A1 | Process for preparing compounds that contain carboxyamide groups, especially peptides | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-07-28 | — | — | EP | disclosed |
| US-4244893-A | FIREPROOFING; FINISHES FOR TEXTILES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-01-13 | — | — | US | disclosed |
| EP-0000024-A1 | Polyadducts containing phosphorus and their application in the flameproofing of textile materials | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-12-20 | — | — | EP | disclosed |