Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 12/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5259564 | 0.71 | TAAR1 (0.37) | SLC6A2SLC6A3CYP2D6KCNH2TAAR1 | |
| SCHEMBL9864166 | 0.68 | SLC6A2 (0.46) | SLC6A2SLC6A3SLC6A4CYP2D6KCNH2 | |
| SCHEMBL5542785 | 0.66 | TAAR1 (0.43) | SLC6A2SLC6A3SLC6A4CYP2D6KCNH2 | |
| SCHEMBL3121546 | 0.66 | SLC6A2 (0.51) | SLC6A2SLC6A3SLC6A4CYP2D6KCNH2 | |
| SCHEMBL6694920 | 0.65 | TAAR1 (0.42) | SLC6A2SLC6A3SLC6A4CYP2D6KCNH2 | |
| SCHEMBL9864544 | 0.65 | TAAR1 (0.42) | SLC6A2SLC6A3SLC6A4CYP2D6KCNH2 | |
| SCHEMBL9870878 | 0.63 | SLC6A2 (0.58) | SLC6A2SLC6A3SLC6A4CYP2D6KCNH2 | |
| SCHEMBL19554785 | 0.63 | TAAR1 (0.51) | SLC6A2SLC6A3SLC6A4CYP2D6KCNH2 | |
| SCHEMBL11432807 | 0.63 | BACE1 (0.51) | SLC6A2SLC6A3SLC6A4CYP2D6KCNH2 | |
| SCHEMBL7004269 | 0.63 | KDM1A (0.48) | SLC6A2SLC6A3CYP2D6KCNH2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047432-A | Antidepressants | THE BOOTS COMPANY PLC (GB) | 1991-09-10 | — | — | US | disclosed |