Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694920 | 0.81 | TAAR1 (0.42) | TAAR1BACE1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9864166 | 0.75 | SLC6A2 (0.46) | TAAR1BACE1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8648535 | 0.74 | MAOB (0.38) | TAAR1SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL5542785 | 0.69 | TAAR1 (0.43) | TAAR1BACE1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3121546 | 0.69 | SLC6A2 (0.51) | TAAR1BACE1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4470188 | 0.68 | ESR2 (0.52) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL5547821 | 0.65 | SLC6A2 (0.50) | TAAR1SLC6A2SLC6A4SLC6A3KCNH2 | |
| Methyl Alcohol SCHEMBL9515250 | 0.65 | SLC6A3 (0.45) | SLC6A2SLC6A4SLC6A3 | |
| Methyl Alcohol SCHEMBL9515247 | 0.65 | SLC6A3 (0.45) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9864341 | 0.65 | SLC6A2 (0.45) | TAAR1BACE1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047432-A | Antidepressants | THE BOOTS COMPANY PLC (GB) | 1991-09-10 | — | — | US | disclosed |