P-Xylene

P-Xylene

SCHEMBL9864343

CCOCCO.Cc1ccc(C)cc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.67
TSHR P16473 2/20 0.41
MAPK1 P28482 2/20 0.41
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
ACHE P22303 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
MMP14 P50281 1/20 0.37
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.37
HTT P42858 2/20 0.37
THRB P10828 1/20 0.37
MAPT P10636 1/20 0.37
GAA P10253 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
NR1I2 O75469 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
USP2 O75604 1/20 0.35
LMNA P02545 1/20 0.35
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Xylene SCHEMBL10927438 0.90 ALDH1A1 (0.54) ALDH1A1TSHRMAPK1MEN1KMT2A
Toluene SCHEMBL8618448 0.89 ALDH1A1 (0.58) ALDH1A1TSHRMAPK1MEN1KMT2A
P-Xylene SCHEMBL18334385 0.87 TSHR (0.56) ALDH1A1TSHRMAPK1MEN1KMT2A
P-Xylene SCHEMBL27968200 0.87 TSHR (0.56) ALDH1A1TSHRMAPK1MEN1KMT2A
Toluene SCHEMBL10898953 0.87 ALDH1A1 (0.56) ALDH1A1TSHRMAPK1MEN1KMT2A
Diethylene Glycol Monoethyl Ether SCHEMBL28056157 0.86 ALDH1A1 (0.54) ALDH1A1TSHRMAPK1MEN1KMT2A
O-Xylene SCHEMBL10662343 0.82 ALDH1A1 (0.61) ALDH1A1TSHRMAPK1MEN1KMT2A
2-Ethoxyethanol SCHEMBL9432157 0.82 ALDH1A1 (1.00) ALDH1A1TSHRMAPK1MEN1KMT2A
2-Ethoxyethanol SCHEMBL11024472 0.82 ALDH1A1 (1.00) ALDH1A1TSHRMAPK1MEN1KMT2A
2-Ethoxyethanol SCHEMBL9547497 0.82 ALDH1A1 (1.00) ALDH1A1TSHRMAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105607422-B Alkali-soluble resin, photosensitive resin composition containing same and application 奇美实业股份有限公司 2019-11-12 CN disclosed
CN-105425542-B Photosensitive resin composition for color filter and application thereof 奇美实业股份有限公司 2019-10-18 CN disclosed
CN-107561861-A Photosensitive resin composition and application thereof 奇美实业股份有限公司 2018-01-09 CN disclosed
CN-106200265-A Photosensitive resin composition, color filter and preparation method thereof, and liquid crystal display device 奇美实业股份有限公司 2016-12-07 CN disclosed
CN-105717747-A Photosensitive resin composition and application thereof 奇美实业股份有限公司 2016-06-29 CN disclosed
EP-0423962-A2 Ethylene polymer compositions NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1991-04-24 EP disclosed
US-4094925-A Compound and its use in synthetic resin mixtures having high reactivity under the action of ionizing rays RUTGERSWERKE AKTIENGESELLSCHAFT (DT) 1978-06-13 US disclosed