Toluene

Toluene

SCHEMBL8618448

CCOCCO.Cc1ccccc1

nearest known ligand 0.58

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.58
TSHR P16473 4/20 0.46
LMNA P02545 1/20 0.46
ALOX12 P18054 1/20 0.46
ACHE P22303 1/20 0.46
RECQL P46063 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.38
RAB9A P51151 1/20 0.38
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
GLA P06280 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MAPK1 P28482 1/20 0.36
KCNH3 Q9ULD8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL10898953 0.98 ALDH1A1 (0.56) ALDH1A1TSHRLMNAALOX12ACHE
Diethylene Glycol Monoethyl Ether SCHEMBL28056157 0.96 ALDH1A1 (0.54) ALDH1A1TSHRLMNAALOX12ACHE
P-Xylene SCHEMBL9864343 0.89 ALDH1A1 (0.67) ALDH1A1TSHRLMNAACHESMN1; SMN2
Toluene SCHEMBL11494092 0.87 TSHR (0.50) ALDH1A1TSHRLMNAALOX12ACHE
Toluene SCHEMBL3648121 0.87 LMNA (0.55) ALDH1A1TSHRLMNAALOX12ACHE
Diethylene Glycol Monoethyl Ether SCHEMBL28397481 0.87 ALDH1A1 (0.44) ALDH1A1TSHRLMNAALOX12ACHE
O-Xylene SCHEMBL10662343 0.85 ALDH1A1 (0.61) ALDH1A1TSHRACHERECQLSMN1; SMN2
Toluene SCHEMBL7649668 0.85 LMNA (0.52) TSHRLMNAALOX12ACHESMN1; SMN2
2-Ethoxyethanol SCHEMBL11703786 0.84 ALDH1A1 (0.82) ALDH1A1TSHRRECQLSMN1; SMN2RAB9A
P-Xylene SCHEMBL10927438 0.84 ALDH1A1 (0.54) ALDH1A1TSHRLMNASMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107206673-A Three-dimensional modeling soluble material 花王株式会社 2017-09-26 CN disclosed
EP-0842251-A1 REDUCED RESIDUE HARD SURFACE CLEANER COMPRISING HYDROTROPE STEPAN COMPANY (US) 1998-05-20 EP disclosed
WO-1997030140-A1 REDUCED RESIDUE HARD SURFACE CLEANER COMPRISING HYDROTROPE STEPAN COMPANY (US) 1997-08-21 WO disclosed
EP-0165508-A2 Metal-containing phenolic coating compositons UNION CARBIDE CORPORATION (US) 1985-12-27 EP disclosed
US-4544688-A CORROSION INHIBITING COATINGS UNION CARBIDE CORP. (US) 1985-10-01 US disclosed