Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 16/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL987403 | 0.86 | VCP (0.39) | VCP | |
| SCHEMBL12585670 | 0.80 | NPC1 (0.39) | VCP | |
| SCHEMBL988519 | 0.80 | VCP (0.39) | VCP | |
| SCHEMBL12585961 | 0.79 | VCP (0.40) | VCP | |
| SCHEMBL12585979 | 0.79 | MMP12 (0.39) | VCP | |
| SCHEMBL988293 | 0.77 | VCP (0.40) | VCP | |
| SCHEMBL12584885 | 0.77 | HDAC3 (0.37) | — | |
| Bicarbonate SCHEMBL16143543 | 0.76 | NPC1 (0.42) | — | |
| SCHEMBL986579 | 0.76 | HDAC3 (0.39) | VCP | |
| SCHEMBL987405 | 0.76 | AR (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2277858-A1 | AMIDE COMPOUND | Astellas Pharma Inc. (JP) | 2011-01-26 | — | — | EP | claimed |