Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL512927 | 0.82 | MEN1 (0.55) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL6820625 | 0.70 | POLB (0.41) | KMT2ASMN1; SMN2LMNAPOLB | |
| SCHEMBL9864525 | 0.69 | MAPT (0.36) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL8864055 | 0.67 | CHRNA4 (0.32) | — | |
| SCHEMBL6405891 | 0.64 | POLB (0.49) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL6802370 | 0.63 | FDPS (0.32) | — | |
| SCHEMBL5859053 | 0.60 | PTPN5 (0.46) | — | |
| SCHEMBL9863815 | 0.59 | MAPT (0.37) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL515676 | 0.59 | ALDH1A1 (0.45) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL513204 | 0.59 | HDAC6 (0.44) | MAPTSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041567-A | Human and veterianary medicine; veneral diseases respiratory diseases, bovine mastitis | BEECHAM GROUP PLC (GB) | 1991-08-20 | — | — | US | disclosed |
| US-4812470-A | Antibacterial monic acid derivatives | BEECHAM GROUP P.L.C. (GB) | 1989-03-14 | — | — | US | disclosed |
| EP-0087953-B1 | ANTIBACTERIAL 1-NORMON-2-YL-HETEROCYCLIC COMPOUNDS | BEECHAM GROUP PLC (GB) | 1988-04-27 | — | — | EP | disclosed |
| EP-0087953-A2 | Antibacterial 1-normon-2-yl-heterocyclic compounds | BEECHAM GROUP PLC (GB) | 1983-09-07 | — | — | EP | disclosed |