Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13025185 | 0.79 | GBA1 (0.42) | KDM4ETSHRNPC1RECQLRAB9A | |
| SCHEMBL942928 | 0.75 | KDM4E (0.40) | KDM4ETSHRCYP2D6GAAALDH1A1 | |
| SCHEMBL1088788 | 0.72 | NPC1 (0.36) | KDM4ENPC1RECQLRAB9AGAA | |
| SCHEMBL17311729 | 0.72 | CYP2D6 (0.40) | KDM4ETSHRCYP2D6GAAL3MBTL1 | |
| SCHEMBL17311731 | 0.72 | CYP2D6 (0.40) | KDM4ETSHRCYP2D6GAAL3MBTL1 | |
| SCHEMBL17311730 | 0.72 | CYP2D6 (0.40) | KDM4ETSHRCYP2D6GAAL3MBTL1 | |
| SCHEMBL17499967 | 0.72 | CYP2D6 (0.40) | KDM4ETSHRCYP2D6GAAL3MBTL1 | |
| SCHEMBL31345606 | 0.72 | KDM4E (0.33) | KDM4ENPC1RECQLRAB9AGAA | |
| SCHEMBL6422416 | 0.72 | ALDH1A1 (0.33) | KDM4ENPC1RECQLRAB9AGAA | |
| SCHEMBL1077813 | 0.72 | KDM4E (0.33) | KDM4ENPC1RECQLRAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009578-A1 | Use Of A Combination Chain Transfer And Activating Agent To Control Molecular Weight And Optical Density Of Pd Catalyzed Norbornene Polymers | PROMERUS LLC (US) | 2011-01-13 | — | — | US | disclosed |
| US-7759439-B2 | Use of a combination chain transfer and activating agent to control molecular weight and optical density of Pd catalyzed norbornene polymers | PROMERUS LLC (US) | 2010-07-20 | — | — | US | disclosed |
| US-20080242810-A1 | Use of a Combination Chain Transfer and Activating Agent to Control Molecular Weight and Optical Density of Pd Catalyzed Norbornene Polymers | PROMERUS LLC (US) | 2008-10-02 | — | — | US | disclosed |