SCHEMBL942928

SCHEMBL942928

O=C(O)C(c1ccccc1)C1CC2C=CC1C2

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.40
TDP1 Q9NUW8 3/20 0.40
ALDH1A1 P00352 1/20 0.40
PKM P14618 1/20 0.40
CYP2D6 P10635 1/20 0.37
SRC P12931 1/20 0.37
TSHR P16473 1/20 0.36
LMNA P02545 3/20 0.36
MAPK1 P28482 1/20 0.36
GAA P10253 1/20 0.35
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21525764 0.91 PTGS2 (0.41) KDM4ETDP1ALDH1A1PKMCYP2D6
SCHEMBL13025185 0.78 GBA1 (0.42) KDM4ETDP1ALDH1A1CYP2D6TSHR
SCHEMBL4682197 0.75 CYP2D6 (0.45) CYP2D6SRCTSHRLMNAMAPK1
SCHEMBL986457 0.75 KDM4E (0.36) KDM4ETDP1ALDH1A1CYP2D6TSHR
SCHEMBL16347967 0.74 CYP2D6 (0.43) KDM4ECYP2D6SRCTSHRLMNA
SCHEMBL16347968 0.74 CYP2D6 (0.43) KDM4ECYP2D6SRCTSHRLMNA
SCHEMBL545557 0.74 APEX1 (0.42) KDM4EALDH1A1TSHR
SCHEMBL14053439 0.70 GRM5 (0.47) KDM4ELMNA
SCHEMBL22941781 0.70 KDM4E (0.39) KDM4ETDP1ALDH1A1LMNAGAA
SCHEMBL3293689 0.70 KDM4E (0.39) KDM4ETDP1ALDH1A1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109313388-B Negative photosensitive composition 住友电木株式会社 2022-06-21 CN disclosed
US-8753790-B2 Self-imageable film forming polymer, compositions thereof and devices and structures made therefrom PROMERUS, LLC (US) 2014-06-17 US disclosed
EP-2448991-B1 A SELF-IMAGEABLE FILM FORMING POLYMER, COMPOSITIONS THEREOF AND DEVICES AND STRUCTURES MADE THEREFROM PROMERUS LLC (US) 2014-02-26 EP disclosed
EP-2448991-A2 A SELF-IMAGEABLE FILM FORMING POLYMER, COMPOSITIONS THEREOF AND DEVICES AND STRUCTURES MADE THEREFROM Promerus, LLC (US) 2012-05-09 EP disclosed
US-20110104614-A1 Self-imageable film forming polymer, compositions thereof and devices and structures made therefrom PROMERUS LLC 2011-05-05 US disclosed
WO-2011002516-A2 A SELF-IMAGEABLE FILM FORMING POLYMER, COMPOSITIONS THEREOF AND DEVICES AND STRUCTURES MADE THEREFROM PROMERUS LLC (US) 2011-01-06 WO disclosed