Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 10/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9864263 | 0.93 | PTAFR (0.47) | PTAFRMEN1ALDH1A1POLBHTT | |
| SCHEMBL9863786 | 0.92 | HDAC3 (0.48) | PTAFRMEN1ALDH1A1POLBHTT | |
| SCHEMBL9864382 | 0.91 | PTAFR (0.52) | PTAFRMEN1ALDH1A1POLBHTT | |
| SCHEMBL9872279 | 0.89 | HDAC3 (0.43) | PTAFRMEN1ALDH1A1POLBHTT | |
| SCHEMBL9864329 | 0.87 | PTAFR (0.48) | PTAFRMEN1ALDH1A1POLBHTT | |
| SCHEMBL9864389 | 0.87 | PTAFR (0.42) | PTAFRMEN1ALDH1A1POLBHTT | |
| SCHEMBL9864142 | 0.86 | PTAFR (0.43) | PTAFRMEN1ALDH1A1POLBHTT | |
| SCHEMBL12228314 | 0.86 | PGR (0.45) | PTAFRMEN1ALDH1A1POLBHTT | |
| SCHEMBL9864670 | 0.85 | PTAFR (0.43) | PTAFRMEN1ALDH1A1POLBHTT | |
| SCHEMBL9864524 | 0.82 | HDAC3 (0.46) | PTAFRMEN1ALDH1A1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407955-A1 | New hetrazepines acting as PAF antagonists, process for their production and their use as drugs | BOEHRINGER INGELHEIM KG (DE) | 1991-01-16 | — | — | EP | disclosed |