Thiobencarb

Thiobencarb

SCHEMBL9864655

C=C(Cl)CSC(=S)N(CC)CC.CCN(CC)C(=O)SCc1ccc(Cl)cc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.57
L3MBTL1 Q9Y468 4/20 0.57
CYP3A4 P08684 1/20 0.57
SMN1; SMN2 Q16637 4/20 0.43
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
LMNA P02545 4/20 0.41
HPGD P15428 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
PHGDH O43175 1/20 0.37
MGLL Q99685 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
MAPT P10636 1/20 0.36
HDAC3 O15379 2/20 0.36
HDAC4 P56524 2/20 0.36
HDAC1 Q13547 2/20 0.36
HDAC7 Q8WUI4 2/20 0.36
HDAC2 Q92769 2/20 0.36
HDAC10 Q969S8 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiobencarb SCHEMBL3629076 0.83 MEN1 (0.50) ALDH1A1L3MBTL1RAB9ALMNAHPGD
Thiobencarb SCHEMBL65110 0.83 MEN1 (0.50) ALDH1A1L3MBTL1RAB9ALMNAHPGD
Thiobencarb SCHEMBL8518444 0.82 HPGD (0.49) ALDH1A1L3MBTL1CYP3A4SMN1; SMN2RAB9A
Thiobencarb SCHEMBL8008188 0.77 IDO1 (0.50) ALDH1A1L3MBTL1NPC1RAB9ALMNA
Thiobencarb SCHEMBL17145066 0.77 IDO1 (0.46) ALDH1A1L3MBTL1CYP3A4LMNAHPGD
Sulfallate SCHEMBL136254 0.76 ALDH1A1 (1.00) ALDH1A1L3MBTL1CYP3A4SMN1; SMN2NPC1
Thiobencarb SCHEMBL27506307 0.75 KMT2A (0.46) ALDH1A1L3MBTL1SMN1; SMN2LMNAHPGD
SCHEMBL11724334 0.75 ALDH1A1 (0.43) ALDH1A1L3MBTL1SMN1; SMN2RAB9ALMNA
SCHEMBL3143432 0.72 MGLL (0.56) ALDH1A1L3MBTL1CYP3A4SMN1; SMN2NPC1
SCHEMBL6304971 0.72 ALDH1A1 (0.60) ALDH1A1L3MBTL1CYP3A4SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4988384-A HERBICIDES, PLANT GROWTH REGULATORS, ANTIGROWTH AGENTS MONSANTO COMPANY (US) 1991-01-29 US disclosed