Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 8/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 4/20 | 0.38 |
| ▸ | FNTB | P49356 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865156 | 0.81 | ALDH1A1 (0.43) | GRIA4PLA2G1BATG4BALDH1A1GRIA2 | |
| SCHEMBL9865339 | 0.77 | FNTA (0.32) | GRIA4ALDH1A1GRIA2HPGDKDM4E | |
| SCHEMBL9865382 | 0.77 | ALDH1A1 (0.36) | ALDH1A1GAAHPGDKDM4EMAPK1 | |
| SCHEMBL9866197 | 0.77 | L3MBTL1 (0.32) | ALDH1A1HPGDKDM4EMAPK1HSD17B10 | |
| SCHEMBL9865539 | 0.75 | ALDH1A1 (0.54) | ALDH1A1GAAHPGDKDM4EMAPK1 | |
| SCHEMBL9864787 | 0.74 | — | — | |
| SCHEMBL9865673 | 0.74 | FNTA (0.48) | GRIA4ALDH1A1GRIA2RAB9AFNTA | |
| SCHEMBL9141734 | 0.70 | GRIA4 (0.51) | GRIA4PLA2G1BATG4BGRIA2FNTA | |
| SCHEMBL5728897 | 0.67 | GRIA4 (0.75) | GRIA4PLA2G1BATG4BGRIA2FNTA | |
| SCHEMBL9865408 | 0.67 | L3MBTL1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994485-A | Seed and soil fungi, bacteria | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1991-02-19 | — | — | US | disclosed |
| EP-0234622-B1 | NEW THIO COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1990-06-27 | — | — | EP | disclosed |
| EP-0234622-A1 | New thio compounds having fungicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1987-09-02 | — | — | EP | disclosed |