Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9337449 | 0.90 | CA1 (0.47) | HDAC8HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL9335520 | 0.84 | CYP2C9 (0.45) | HDAC8HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL9335827 | 0.83 | CA1 (0.45) | HDAC8HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL9335641 | 0.83 | LTA4H (0.37) | HDAC8HDAC1HDAC2LTA4HLRRK2 | |
| SCHEMBL9866032 | 0.81 | CA1 (0.50) | HDAC8HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL9335876 | 0.79 | LTA4H (0.44) | HDAC8HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL9337569 | 0.79 | LTA4H (0.54) | HDAC8HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL9339470 | 0.78 | MEN1 (0.42) | LRRK2NPC1RAB9A | |
| SCHEMBL9335648 | 0.76 | LRRK2 (0.46) | LRRK2CYP2C9PTGER1NPC1RAB9A | |
| SCHEMBL18326993 | 0.73 | CA1 (0.49) | HDAC8HDAC3HDAC1HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |