Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 14/20 | 1.00 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.72 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.71 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.71 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.71 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.71 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.71 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.71 |
| ▸ | CCKAR | P32238 | 4/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9864922 | 1.00 | CCKBR (1.00) | CCKBRSCN9APSEN1PSEN2APH1B | |
| SCHEMBL7207460 | 0.88 | CCKBR (0.78) | CCKBRCCKAR | |
| SCHEMBL2927644 | 0.88 | CCKBR (0.78) | CCKBRCCKAR | |
| SCHEMBL6309196 | 0.88 | CCKBR (0.77) | CCKBRSCN9APSEN1PSEN2APH1B | |
| SCHEMBL9865804 | 0.86 | CCKBR (1.00) | CCKBR | |
| SCHEMBL7213169 | 0.85 | CCKBR (0.85) | CCKBRCCKAR | |
| SCHEMBL9468526 | 0.84 | CCKBR (0.72) | CCKBRCCKAR | |
| SCHEMBL8617432 | 0.84 | HDAC3 (0.75) | CCKBRPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9868120 | 0.84 | CCKBR (1.00) | CCKBRCCKAR | |
| SCHEMBL9868116 | 0.84 | CCKBR (1.00) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5004741-A | Cholecystokinin(CCK); Treating Disorders Of The Gastrointestinal Tract, Central Nervous System And Of The Appetite Of Animals | MERCK & CO., INC. (US) | 1991-04-02 | — | — | US | disclosed |
| EP-0284256-A1 | Benzodiazepine analogs | MERCK & CO. INC. (US) | 1988-09-28 | — | — | EP | disclosed |