Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | FNTA | P49354 | 7/20 | 0.42 |
| ▸ | FNTB | P49356 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9864961 | 0.87 | ALDH1A1 (0.69) | KDM4EALDH1A1HPGDGAALMNA | |
| SCHEMBL9865517 | 0.81 | MEN1 (0.55) | KDM4EALDH1A1HPGDGAALMNA | |
| SCHEMBL9864830 | 0.79 | ALDH1A1 (0.68) | KDM4EALDH1A1HPGDGAALMNA | |
| SCHEMBL9865583 | 0.77 | GRIA4 (0.48) | KDM4EALDH1A1HPGDGAANPSR1 | |
| SCHEMBL10652875 | 0.77 | GRIA4 (0.74) | GRIA4KMT2AFNTAFNTBGRIA2 | |
| SCHEMBL9865192 | 0.74 | MEN1 (0.76) | KDM4EALDH1A1HPGDGAALMNA | |
| SCHEMBL9865433 | 0.73 | GRIA4 (0.56) | KDM4EALDH1A1HPGDGAALMNA | |
| SCHEMBL6802135 | 0.72 | ALDH1A1 (0.64) | KDM4EALDH1A1HPGDGAALMNA | |
| SCHEMBL9865438 | 0.71 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDGAALMNA | |
| SCHEMBL16792140 | 0.68 | GRIA4 (0.64) | NPSR1GRIA4KMT2AFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994485-A | Seed and soil fungi, bacteria | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1991-02-19 | — | — | US | disclosed |
| EP-0234622-B1 | NEW THIO COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1990-06-27 | — | — | EP | disclosed |
| EP-0234622-A1 | New thio compounds having fungicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1987-09-02 | — | — | EP | disclosed |