Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.42 |
| ▸ | CNR1 | P21554 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 2/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11473706 | 0.92 | EPHX1 (0.40) | CNR2CNR1HPGDEPHX1CASP3 | |
| SCHEMBL30404411 | 0.89 | CASP3 (0.38) | CNR2CNR1HPGDEPHX1CASP3 | |
| SCHEMBL6625677 | 0.89 | CASP3 (0.38) | CNR2CNR1HPGDEPHX1CASP3 | |
| SCHEMBL15919532 | 0.80 | HPGD (0.40) | HPGDEPHX1CASP3PREPFKBP1A | |
| SCHEMBL31040357 | 0.79 | EPHX1 (0.51) | CNR2CNR1HPGDEPHX1PREP | |
| SCHEMBL24434718 | 0.78 | POLB (0.44) | CNR2CNR1FKBP1A | |
| SCHEMBL2261903 | 0.78 | CASP3 (0.43) | HPGDEPHX1CASP3PREPFKBP1A | |
| SCHEMBL17595518 | 0.78 | HPGD (0.41) | HPGDEPHX1CASP3PREPFKBP1A | |
| SCHEMBL17595517 | 0.78 | HPGD (0.41) | HPGDEPHX1CASP3PREPFKBP1A | |
| SCHEMBL29894062 | 0.78 | HPGD (0.41) | HPGDEPHX1CASP3PREPFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5061722-A | Hypotensive agents; e.g. ramipril | HOECHST AG (DE) | 1991-10-29 | — | — | US | disclosed |
| US-5053519-A | Hypotensive agents; diuretics; vasodilation | HOECHST AG (DE) | 1991-10-01 | — | — | US | disclosed |
| US-4879403-A | AMINATION, CRYSTALLIZATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-11-07 | — | — | US | disclosed |
| US-4727160-A | HYPOTENSIVE INTERMEDIATES | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-02-23 | — | — | US | disclosed |