Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865364 | 0.93 | TSHR (0.53) | TSHRUSP2ALDH1A1HTR6LMNA | |
| SCHEMBL9002375 | 0.84 | TSHR (0.60) | TSHRUSP2ALDH1A1LMNAPOLB | |
| SCHEMBL9865614 | 0.84 | TSHR (0.48) | TSHRUSP2ALDH1A1HTR6LMNA | |
| SCHEMBL9866239 | 0.84 | TSHR (0.42) | TSHRUSP2ALDH1A1 | |
| SCHEMBL9832562 | 0.82 | TSHR (0.58) | TSHRUSP2ALDH1A1LMNAPOLB | |
| SCHEMBL10664738 | 0.80 | TSHR (0.45) | TSHRUSP2ALDH1A1 | |
| SCHEMBL10662004 | 0.79 | TSHR (0.56) | TSHRUSP2ALDH1A1LMNA | |
| SCHEMBL9865410 | 0.79 | TSHR (0.47) | TSHRUSP2ALDH1A1HTR6LMNA | |
| SCHEMBL10416986 | 0.78 | TSHR (0.52) | TSHRUSP2ALDH1A1LMNAPOLB | |
| SCHEMBL7910513 | 0.78 | TSHR (0.64) | TSHRUSP2ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013351-A | Triazolo-pyrimidine-2-sulphonamides useful as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-05-07 | — | — | US | claimed |
| US-5013351-A | Triazolo-pyrimidine-2-sulphonamides useful as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-05-07 | — | — | US | disclosed |