Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CCR4 | P51679 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865133 | 0.84 | TSHR (0.48) | TSHRALDH1A1USP2 | |
| SCHEMBL9865614 | 0.82 | TSHR (0.48) | TSHRALDH1A1USP2 | |
| SCHEMBL9002375 | 0.78 | TSHR (0.60) | TSHRALDH1A1USP2PKM | |
| SCHEMBL10562478 | 0.77 | TSHR (0.34) | TSHRSMN1; SMN2CCR4 | |
| SCHEMBL9866247 | 0.77 | PKM (0.34) | TSHRALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL9832562 | 0.76 | TSHR (0.58) | TSHRALDH1A1USP2KDM4EHSD17B10 | |
| SCHEMBL9865364 | 0.76 | TSHR (0.53) | TSHRALDH1A1USP2 | |
| SCHEMBL10662004 | 0.75 | TSHR (0.56) | TSHRALDH1A1USP2CCR4 | |
| SCHEMBL9831332 | 0.74 | ALDH1A1 (0.44) | TSHRALDH1A1USP2SMN1; SMN2KDM4E | |
| SCHEMBL10664738 | 0.73 | TSHR (0.45) | TSHRALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013351-A | Triazolo-pyrimidine-2-sulphonamides useful as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-05-07 | — | — | US | disclosed |
| EP-0268951-A2 | Triazolopyrimidine-2-sulphone amides | BAYER AG (DE) | 1988-06-01 | — | — | EP | disclosed |