Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9002375 | 0.84 | TSHR (0.60) | TSHRUSP2ALDH1A1LMNAPOLB | |
| SCHEMBL9865133 | 0.84 | TSHR (0.48) | TSHRUSP2ALDH1A1HTR6LMNA | |
| SCHEMBL10562478 | 0.83 | TSHR (0.34) | TSHRKMT2AFFAR4 | |
| SCHEMBL9866239 | 0.82 | TSHR (0.42) | TSHRUSP2ALDH1A1 | |
| SCHEMBL9832562 | 0.82 | TSHR (0.58) | TSHRUSP2ALDH1A1LMNAPOLB | |
| SCHEMBL9831332 | 0.79 | ALDH1A1 (0.44) | TSHRUSP2ALDH1A1KMT2A | |
| SCHEMBL7910513 | 0.78 | TSHR (0.64) | TSHRUSP2ALDH1A1LMNAPOLB | |
| SCHEMBL9869243 | 0.77 | TSHR (0.60) | TSHRUSP2ALDH1A1LMNAPOLB | |
| SCHEMBL9833361 | 0.77 | TSHR (0.42) | TSHRUSP2ALDH1A1POLBMEN1 | |
| SCHEMBL9865416 | 0.77 | TDP1 (0.43) | TSHRUSP2ALDH1A1HTR6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013351-A | Triazolo-pyrimidine-2-sulphonamides useful as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-05-07 | — | — | US | disclosed |
| EP-0268951-A2 | Triazolopyrimidine-2-sulphone amides | BAYER AG (DE) | 1988-06-01 | — | — | EP | disclosed |