SCHEMBL9865136

SCHEMBL9865136

C[S+]([O-])c1sc(C=O)cc1C=O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.33
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9864870 0.75 CYP2A6 (0.30) CYP2A6
SCHEMBL9865145 0.64 ALDH1A1 (0.66) CYP2A6ALDH1A1
SCHEMBL10567667 0.61 TDP1 (0.41) CYP2A6ALDH1A1
SCHEMBL13084791 0.59 CYP2A6 (0.56) CYP2A6ALDH1A1
SCHEMBL5404708 0.58 ATM (0.38)
SCHEMBL535964 0.57 LMNA (0.50) ALDH1A1
Dimethyl Sulfoxide SCHEMBL27655651 0.57 LMNA (0.44) CYP2A6ALDH1A1
SCHEMBL2222194 0.57
SCHEMBL21491325 0.57 TDP1 (0.38) ALDH1A1
SCHEMBL27522167 0.57 TDP1 (0.52) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1017243-B THIO COMPOUNDS HAVING FUNGICIDAL ACTIVITY DUPHAR INT RES (NL) 1992-07-01 CN disclosed
US-4994485-A Seed and soil fungi, bacteria DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1991-02-19 US disclosed
EP-0234622-B1 NEW THIO COMPOUNDS HAVING FUNGICIDAL ACTIVITY DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1990-06-27 EP disclosed
CN-87101917-A Has the active novel sulfurized compound of antifungal 1988-01-06 CN disclosed
EP-0234622-A1 New thio compounds having fungicidal activity DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1987-09-02 EP disclosed