Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL195275 | 0.88 | TSHR (0.37) | TSHRNFKB1CYP2C19MEN1KMT2A | |
| SCHEMBL4336157 | 0.84 | KMT2A (0.38) | TSHRNFKB1CYP2C19MEN1KMT2A | |
| SCHEMBL6013601 | 0.84 | KMT2A (0.38) | TSHRNFKB1CYP2C19MEN1KMT2A | |
| SCHEMBL194968 | 0.82 | NAAA (0.38) | TSHRNFKB1CYP2C19MEN1KMT2A | |
| SCHEMBL27703376 | 0.82 | NAAA (0.38) | TSHRNFKB1CYP2C19MEN1KMT2A | |
| SCHEMBL28288158 | 0.82 | NAAA (0.38) | TSHRNFKB1CYP2C19MEN1KMT2A | |
| SCHEMBL1931454 | 0.82 | TSHR (0.34) | TSHRNFKB1CYP2C19 | |
| SCHEMBL3632253 | 0.81 | LMNA (0.39) | TSHRNFKB1CYP2C19MEN1KMT2A | |
| SCHEMBL9865161 | 0.78 | TSHR (0.44) | TSHRNFKB1CYP2C19KMT2AGAA | |
| SCHEMBL986872 | 0.78 | TSHR (0.41) | TSHRNFKB1CYP2C19CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912514-A1 | NOVEL STERICALLY HINDERED PIPERIDINE DERIVATIVES ACTING AS LIGHT STABILISERS FOR POLYMERS | Clariant GmbH (DE) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997042171-A1 | NOVEL STERICALLY HINDERED PIPERIDINE DERIVATIVES ACTING AS LIGHT STABILISERS FOR POLYMERS | CLARIANT GMBH (DE) | 1997-11-13 | — | — | WO | disclosed |