Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | LDLR | P01130 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 2/20 | 0.36 |
| ▸ | ESRRG | P62508 | 2/20 | 0.36 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MDH1 | P40925 | 1/20 | 0.35 |
| ▸ | MDH2 | P40926 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9339491 | 0.92 | HDAC1 (0.51) | HDAC1F10PRSS1MAPTSMN1; SMN2 | |
| SCHEMBL9339500 | 0.85 | ACHE (0.49) | HDAC1F10PRSS1MAPTSMN1; SMN2 | |
| SCHEMBL9866208 | 0.83 | BRD4 (0.44) | HDAC1MAPTSMN1; SMN2NR1H4 | |
| SCHEMBL7307840 | 0.80 | CA1 (0.46) | PRSS1CD274 | |
| SCHEMBL9336123 | 0.78 | ACHE (0.49) | HDAC1F10PRSS1MAPTNR1H4 | |
| SCHEMBL9335835 | 0.78 | BRD4 (0.45) | HDAC1MAPTSMN1; SMN2NR1H4 | |
| SCHEMBL2659302 | 0.74 | CD274 (0.56) | HDAC1PRSS1MAPTSMN1; SMN2CD274 | |
| SCHEMBL7302006 | 0.74 | SYK (0.46) | PRSS1MAPTSMN1; SMN2 | |
| SCHEMBL9339289 | 0.73 | MEN1 (0.43) | HDAC1NR1H4 | |
| SCHEMBL8382918 | 0.73 | ATM (0.48) | HDAC1PRSS1MAPTNR1H4PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |