Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866163 | 0.96 | RAB9A (0.37) | RAB9AEPHX2 | |
| SCHEMBL9865744 | 0.94 | PMP22 (0.40) | — | |
| SCHEMBL9865426 | 0.94 | NAMPT (0.38) | — | |
| SCHEMBL9865155 | 0.94 | BLM (0.40) | — | |
| SCHEMBL9866078 | 0.94 | EPHX2 (0.39) | EPHX2 | |
| SCHEMBL9865305 | 0.93 | NPY1R (0.41) | — | |
| SCHEMBL7431291 | 0.93 | EPHX2 (0.41) | RAB9AEPHX2 | |
| SCHEMBL7431296 | 0.93 | EPHX2 (0.41) | RAB9AEPHX2 | |
| SCHEMBL7286314 | 0.92 | — | — | |
| SCHEMBL7311686 | 0.92 | NPY1R (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021431-A | H-1 antagonist, h-2 agonist for treating hypertension, cardiac disease or arterial occlusion | HEUMANN PHARMA GMBH & CO. (DE) | 1991-06-04 | — | — | US | disclosed |
| EP-0199845-B1 | IMIDAZOLYLALKYLGUANIDIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HEUMANN PHARMA GMBH & CO (DE) | 1990-08-01 | — | — | EP | disclosed |
| EP-0199845-A1 | Imidazolylalkylguanidin derivatives, process for their preparation and pharmaceutical compositions containing them | HEUMANN PHARMA GMBH & CO (DE) | 1986-11-05 | — | — | EP | disclosed |