SCHEMBL7311686

SCHEMBL7311686

O=C(NC(=NCCC(c1cccc(F)c1)c1ccccn1)NCCCc1c[nH]cn1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPY1R P25929 1/20 0.39
OPRM1 P35372 1/20 0.35
OPRL1 P41146 1/20 0.35
NAMPT P43490 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7296401 0.94 NPY1R (0.45) NPY1RNAMPT
SCHEMBL9865299 0.92 RAB9A (0.38)
SCHEMBL9865426 0.92 NAMPT (0.38) NPY1RNAMPT
SCHEMBL7312444 0.91 NPY1R (0.36) NPY1R
SCHEMBL7286314 0.91
SCHEMBL9866163 0.88 RAB9A (0.37) NPY1R
SCHEMBL7288755 0.88 S1PR3 (0.38)
SCHEMBL7303037 0.88 NPY1R (0.36) NPY1R
SCHEMBL9867599 0.88 NPY1R (0.39) NPY1RNAMPT
SCHEMBL9865744 0.87 PMP22 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0262448-A1 Imidazolylguanidine derivatives, process for their preparation and medicines containing them HEUMANN PHARMA GMBH & CO (DE) 1988-04-06 EP disclosed