Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL101646 | 0.94 | TSHR (0.50) | RAB9ANPC1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL99379 | 0.85 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL101223 | 0.84 | HDAC1 (0.51) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL15822069 | 0.82 | HDAC1 (0.44) | RAB9ANPC1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL661253 | 0.81 | CHRM3 (0.54) | — | |
| SCHEMBL100635 | 0.81 | MEN1 (0.48) | RAB9ANPC1GAAKMT2AMEN1 | |
| Iodide SCHEMBL98204 | 0.81 | NPC1 (0.42) | RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL101623 | 0.81 | HDAC2 (0.48) | SMN1; SMN2ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL100918 | 0.80 | AKR1C3 (0.46) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL101215 | 0.80 | NPC1 (0.47) | RAB9ANPC1GAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426121-A1 | QUATERNARY AMMONIUM SALT COMPOUND | Teijin Pharma Limited (JP) | 2012-03-07 | — | — | EP | claimed |