SCHEMBL9865307

SCHEMBL9865307

CC1Cc2sccc2/C1=N/O

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.44
NOS2 P35228 4/20 0.34
NOS3 P29474 3/20 0.34
HPGD P15428 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9865315 1.00 USP2 (0.44) USP2NOS2NOS3HPGDKMT2A
SCHEMBL9865556 0.71 ACHE (0.47) NOS2NOS3
SCHEMBL6101892 0.69 USP2 (0.41) USP2NOS2
SCHEMBL354098 0.68 ACHE (0.53) NOS2NOS3HPGDKMT2A
SCHEMBL5970427 0.68 ACHE (0.53) NOS2NOS3HPGDKMT2A
SCHEMBL8349907 0.65
SCHEMBL6644355 0.64 USP2 (0.78) USP2NOS2HPGDKMT2A
SCHEMBL11675005 0.62 EDNRB (0.40) NOS2NOS3KMT2A
SCHEMBL15606100 0.62 HTR2C (0.39) NOS2NOS3HPGDKMT2A
SCHEMBL3578601 0.62 USP2 (0.92) USP2NOS2HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0347378-A1 Imidazole derivatives CIBA-GEIGY AG (CH) 1989-12-20 EP claimed
US-4992090-A Herbicidally active 5,6-dihydrocyclopentathiophenyl-imidazole derivatives CIBA-GEIGY CORPORATION (US) 1991-02-12 US disclosed