Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 10/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866706 | 0.80 | SMN1; SMN2 (0.53) | L3MBTL1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL9865333 | 0.78 | CA1 (0.48) | L3MBTL1CASRHDAC2HDAC8HDAC6 | |
| SCHEMBL27545217 | 0.77 | MEN1 (0.55) | L3MBTL1CASRMEN1KMT2ANPC1 | |
| SCHEMBL11632238 | 0.77 | L3MBTL1 (0.66) | L3MBTL1CASRMEN1KMT2ANPC1 | |
| SCHEMBL9865141 | 0.75 | HTT (0.48) | CASRHDAC8HDAC1MEN1KMT2A | |
| SCHEMBL9865970 | 0.73 | KDM4C (0.50) | HDAC2HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL9865796 | 0.73 | SELL (0.47) | L3MBTL1CASRHDAC2HDAC8HDAC6 | |
| SCHEMBL11632613 | 0.72 | CASR (0.55) | L3MBTL1CASRMEN1KMT2ANPC1 | |
| SCHEMBL9866212 | 0.72 | KMT2A (0.39) | L3MBTL1MEN1KMT2AMAPTLMNA | |
| SCHEMBL1186353 | 0.70 | MEN1 (0.50) | CASRMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |