Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865796 | 0.89 | SELL (0.47) | ALDH1A1SMN1; SMN2LMNAHDAC1HDAC8 | |
| SCHEMBL9866706 | 0.81 | SMN1; SMN2 (0.53) | HTTNPC1ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL9866777 | 0.81 | ALDH1A1 (0.47) | NPC1ALDH1A1CYP2C9CYP2C19RAB9A | |
| SCHEMBL9865135 | 0.76 | HTT (0.51) | HTTNPC1ALOX12ALDH1A1SMN1; SMN2 | |
| SCHEMBL9865340 | 0.75 | L3MBTL1 (0.41) | HTTNPC1ALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL9865970 | 0.74 | KDM4C (0.50) | ALDH1A1CYP2D6HDAC1HDAC8MEN1 | |
| SCHEMBL7135619 | 0.69 | EPHX2 (0.36) | HTTRAB9ALMNAHDAC1HDAC8 | |
| SCHEMBL9866039 | 0.69 | LTA4H (0.46) | NPC1ALDH1A1RAB9AHDAC1HDAC8 | |
| SCHEMBL30308703 | 0.69 | HPGD (0.51) | HTTNPC1ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL25561084 | 0.69 | HPGD (0.51) | HTTNPC1ALDH1A1SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |