Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9771015 | 0.87 | SCN8A (0.31) | — | |
| SCHEMBL9771031 | 0.86 | DRD2 (0.36) | EBPSIGMAR1DRD2DRD4DRD3 | |
| SCHEMBL9771089 | 0.85 | DRD2 (0.47) | DRD2DRD4DRD3SLC6A3 | |
| SCHEMBL9827663 | 0.85 | ALDH1A1 (0.40) | — | |
| SCHEMBL9827438 | 0.85 | ALDH1A1 (0.40) | — | |
| Maleic Acid SCHEMBL9771150 | 0.85 | TAAR1 (0.37) | EBPSIGMAR1DRD2DRD4DRD3 | |
| SCHEMBL9866282 | 0.83 | EBP (0.52) | EBPSIGMAR1 | |
| SCHEMBL9865431 | 0.83 | EPHX2 (0.33) | — | |
| SCHEMBL9865982 | 0.79 | NPC1 (0.44) | — | |
| SCHEMBL10874397 | 0.79 | CHRM2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021431-A | H-1 antagonist, h-2 agonist for treating hypertension, cardiac disease or arterial occlusion | HEUMANN PHARMA GMBH & CO. (DE) | 1991-06-04 | — | — | US | claimed |