Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | THRA | P10827 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA6 | P23280 | 2/20 | 0.37 |
| ▸ | COL1A1 | P02452 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9121357 | 0.88 | PARP15 (0.47) | ALDH1A1KDM4ETHRATHRBPARP15 | |
| SCHEMBL9122043 | 0.78 | KMT2A (0.47) | ALDH1A1THRATHRBPARP15PARP10 | |
| SCHEMBL26684938 | 0.74 | CNR2 (0.43) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL14834850 | 0.74 | ALDH1A1 (0.45) | ALDH1A1KDM4EPARP15PARP10MEN1 | |
| SCHEMBL7324207 | 0.74 | PDE4B (0.56) | CA2 | |
| SCHEMBL20970869 | 0.74 | HTR2A (0.64) | KDM4E | |
| SCHEMBL24951301 | 0.73 | KMT2A (0.52) | ALDH1A1KDM4EPARP15PARP10MEN1 | |
| SCHEMBL26684865 | 0.72 | HTR2A (0.43) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL1706883 | 0.72 | PTGS2 (0.64) | KDM4E | |
| SCHEMBL7725064 | 0.70 | KMT2A (0.43) | ALDH1A1THRATHRBPARP15PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037827-A | Useful for treatment of disease caused by platelet activating factory | EISAI CO., LTD. (JP) | 1991-08-06 | — | — | US | disclosed |