Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 7/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 7/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 7/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 7/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 7/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.38 |
| ▸ | CHRNG | P07510 | 5/20 | 0.38 |
| ▸ | CHRND | Q07001 | 5/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865819 | 0.86 | CHRNA1 (0.32) | SLC6A3CHRNA1CHRNB1CHRNB2SLC6A2 | |
| SCHEMBL9577875 | 0.81 | HTR2C (0.41) | SLC6A3CHRNA1CHRNB1CHRNB2SLC6A2 | |
| SCHEMBL10561360 | 0.77 | HTR2C (0.38) | SLC6A3CHRNA1CHRNB1CHRNB2SLC6A2 | |
| SCHEMBL9819493 | 0.73 | SLC6A3 (0.44) | SLC6A3CHRNA1CHRNB1CHRNB2SLC6A2 | |
| SCHEMBL9865234 | 0.72 | — | — | |
| SCHEMBL7787371 | 0.71 | HTR2C (0.43) | SLC6A3CHRNA1CHRNB1CHRNB2SLC6A2 | |
| SCHEMBL9866573 | 0.70 | CHRNA1 (0.31) | SLC6A3CHRNA1CHRNB1CHRNB2SLC6A2 | |
| SCHEMBL9864892 | 0.69 | THRB (0.39) | SCN5A | |
| SCHEMBL19814395 | 0.68 | PARP1 (0.43) | SLC6A3CHRNA1CHRNB1CHRNB2SLC6A2 | |
| SCHEMBL27521110 | 0.68 | SLC6A3 (0.43) | SLC6A3CHRNA1CHRNB1CHRNB2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4929268-A | HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1990-05-29 | — | — | US | claimed |
| US-5006151-A | Herbicides | THE DOW CHEMICAL COMPANY (US) | 1991-04-09 | — | — | US | disclosed |
| US-4929268-A | HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1990-05-29 | — | — | US | disclosed |