Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 4/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | GPX4 | P36969 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865550 | 0.99 | MEN1 (0.43) | MEN1LMNAMAPTKMT2AGRIN2B | |
| SCHEMBL30149565 | 0.75 | HTR2A (0.51) | GRIN2BHTR2AHTR2CSIGMAR1DRD2 | |
| SCHEMBL9206013 | 0.75 | DRD1 (0.43) | GRIN2BHTR2AHTR2CSIGMAR1DRD2 | |
| Hydrochloric Acid SCHEMBL30149473 | 0.74 | HTR2A (0.53) | GRIN2BHTR2AHTR2CSIGMAR1TAAR1 | |
| SCHEMBL9866845 | 0.74 | DRD1 (0.42) | LMNAKMT2AGRIN2BHTR2AHTR2C | |
| SCHEMBL10924004 | 0.71 | GRIN2B (0.70) | GRIN2BHTR2AHTR2CDRD2HTR7 | |
| SCHEMBL14863014 | 0.70 | MAPKAPK2 (0.62) | HTR2AHTR2CKDM4EHTR5ANISCH | |
| SCHEMBL31020939 | 0.68 | HTR2A (0.44) | GRIN2BHTR2AHTR2CKDM4EHTR5A | |
| SCHEMBL5613534 | 0.67 | HTR2A (0.46) | HTR2AHTR2CNR2E1SIGMAR1TAAR1 | |
| SCHEMBL9866986 | 0.63 | MAPT (0.39) | MEN1LMNAMAPTKMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999359-A | Analgesics | DR. LO ZAMBELETTI S.P.A. (IT) | 1991-03-12 | — | — | US | disclosed |