Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9206013 | 0.99 | DRD1 (0.43) | DRD1DRD2DRD5HTR2AHTR2C | |
| SCHEMBL9865550 | 0.75 | MEN1 (0.43) | DRD1DRD2HTR2AHTR2CKDM4E | |
| SCHEMBL30149565 | 0.75 | HTR2A (0.51) | DRD2HTR2AHTR2CGRIN2BDRD3 | |
| Hydrochloric Acid SCHEMBL30149473 | 0.74 | HTR2A (0.53) | HTR2AHTR2CGRIN2B | |
| SCHEMBL9865545 | 0.74 | MEN1 (0.42) | DRD1DRD2HTR2AHTR2CKDM4E | |
| SCHEMBL329828 | 0.71 | OPRM1 (0.57) | KDM4EALDH1A1LMNA | |
| SCHEMBL329925 | 0.71 | OPRM1 (0.57) | KDM4EALDH1A1LMNA | |
| SCHEMBL330238 | 0.71 | OPRM1 (0.57) | KDM4EALDH1A1LMNA | |
| SCHEMBL14863014 | 0.70 | MAPKAPK2 (0.62) | DRD1DRD2HTR2AHTR2CKDM4E | |
| SCHEMBL3453173 | 0.69 | OPRM1 (0.56) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999359-A | Analgesics | DR. LO ZAMBELETTI S.P.A. (IT) | 1991-03-12 | — | — | US | disclosed |