Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866845 | 0.99 | DRD1 (0.42) | DRD1DRD2DRD5GRIN2BCASP1 | |
| SCHEMBL30149565 | 0.76 | HTR2A (0.51) | DRD2GRIN2BHTR2AHTR2CDRD3 | |
| SCHEMBL9865550 | 0.76 | MEN1 (0.43) | DRD1DRD2GRIN2BHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL30149473 | 0.75 | HTR2A (0.53) | GRIN2BHTR2AHTR2CSIGMAR1 | |
| SCHEMBL9865545 | 0.75 | MEN1 (0.42) | DRD1DRD2GRIN2BHTR2AHTR2C | |
| SCHEMBL14863014 | 0.70 | MAPKAPK2 (0.62) | DRD1DRD2HTR2AHTR2CSIGMAR1 | |
| SCHEMBL3453173 | 0.70 | OPRM1 (0.56) | — | |
| SCHEMBL329828 | 0.69 | OPRM1 (0.57) | — | |
| SCHEMBL329925 | 0.69 | OPRM1 (0.57) | — | |
| SCHEMBL31020939 | 0.69 | HTR2A (0.44) | DRD1DRD2GRIN2BHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0333427-B1 | Heterocyclic derivatives | SMITHKLINE BEECHAM FARMA (IT) | 1995-08-23 | — | — | EP | claimed |
| US-4999359-A | Analgesics | DR. LO ZAMBELETTI S.P.A. (IT) | 1991-03-12 | — | — | US | disclosed |