Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.39 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.39 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19006409 | 0.91 | CYP4F2 (0.45) | CYP1A2CYP4F2CYP4A11TOP2ACYP4Z1 | |
| SCHEMBL5295531 | 0.81 | MEN1 (0.51) | SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL19013804 | 0.76 | CYP4F2 (0.43) | CYP1A2CYP4F2CYP4A11TOP2ACYP4Z1 | |
| SCHEMBL3884465 | 0.73 | CYP4F2 (0.48) | CYP1A2CYP4F2CYP4A11ALOX5CYP3A4 | |
| SCHEMBL15821166 | 0.71 | CYP4F2 (0.46) | CYP1A2CYP4F2CYP4A11ALOX5CYP3A4 | |
| SCHEMBL27408432 | 0.71 | ALDH1A1 (0.51) | CYP1A2SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL5759014 | 0.71 | CYP4F2 (0.41) | CYP4F2CYP4A11TOP2ACYP4Z1CYSLTR2 | |
| SCHEMBL3928245 | 0.71 | CYP1A2 (0.44) | CYP1A2CYP4F2CYP4A11ALOX5CYP3A4 | |
| SCHEMBL4385060 | 0.70 | CYP1A2 (0.46) | CYP1A2CYP4F2CYP4A11ALOX5CYP3A4 | |
| SCHEMBL1859504 | 0.70 | CYP1A2 (0.57) | CYP1A2CYP4F2CYP4A11ALOX5CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045561-A | Substituted furan sulfonamides as antiglaucoma agents | MERCK & CO., INC. (US) | 1991-09-03 | — | — | US | disclosed |